| Item Type | Name |
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Concept
|
Age Factors
|
|
Concept
|
Blood Flow Velocity
|
|
Concept
|
Alleles
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cations, Divalent
|
|
Concept
|
Biopsy
|
|
Concept
|
Embryonic Induction
|
|
Concept
|
Bradycardia
|
|
Concept
|
Chromosomes, Human, Pair 1
|
|
Concept
|
Chick Embryo
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Chromosome Mapping
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
Cleft Palate
|
|
Concept
|
Coronary Artery Disease
|
|
Concept
|
Homozygote
|
|
Concept
|
DNA Nucleotidyltransferases
|
|
Concept
|
Cysteine Endopeptidases
|
|
Concept
|
DNA, Bacterial
|
|
Concept
|
Down Syndrome
|
|
Concept
|
DNA, Recombinant
|
|
Concept
|
Echocardiography
|
|
Concept
|
Ductus Arteriosus, Patent
|
|
Concept
|
Cardiomegaly
|
|
Concept
|
Lac Operon
|
|
Concept
|
Electrophysiology
|
|
Concept
|
DNA, Superhelical
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Electrocardiography
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Glycogen Storage Disease
|
|
Concept
|
Genes, Lethal
|
|
Concept
|
Genetic Complementation Test
|
|
Concept
|
DNA (Cytosine-5-)-Methyltransferases
|
|
Concept
|
Heart Septal Defects, Atrial
|
|
Concept
|
Hematopoietic Stem Cells
|
|
Concept
|
Hypertrophy
|
|
Concept
|
Escherichia coli
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Isoenzymes
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Purpura, Thrombocytopenic
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
|
Concept
|
Mutation
|
|
Concept
|
Myocardial Contraction
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
Pedigree
|
|
Concept
|
Embryonic and Fetal Development
|
|
Concept
|
Procainamide
|
|
Concept
|
Plasmids
|
|
Concept
|
Poliomyelitis
|
|
Concept
|
Forecasting
|
|
Concept
|
Risk Factors
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
RNA Splicing
|
|
Concept
|
Risk
|
|
Concept
|
Hemodynamics
|
|
Concept
|
Humans
|
|
Concept
|
Single-Blind Method
|
|
Concept
|
Genome
|
|
Concept
|
Truncus Arteriosus
|
|
Concept
|
Ultrasonography
|
|
Concept
|
Trisomy
|
|
Concept
|
Tamoxifen
|
|
Concept
|
Genetic Variation
|
|
Concept
|
Zygote
|
|
Concept
|
Sodium Channels
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Chromosomes, Artificial, Bacterial
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Atrial Function
|
|
Concept
|
Extracellular Matrix Proteins
|
|
Concept
|
Vacuolar Proton-Translocating ATPases
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Mortality
|
|
Concept
|
Chromosomes, Mammalian
|
|
Concept
|
Sequence Alignment
|
|
Concept
|
Sequence Analysis, DNA
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Morphogenesis
|
|
Concept
|
Point Mutation
|
|
Concept
|
Hypertrophy, Left Ventricular
|
|
Concept
|
Retinal Rod Photoreceptor Cells
|
|
Concept
|
Sequence Deletion
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Gene Expression Regulation, Developmental
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Transgenes
|
|
Concept
|
Gene Regulatory Networks
|
|
Concept
|
Chemokines, CC
|
|
Concept
|
Cardiomyopathy, Hypertrophic, Familial
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Gene Knockout Techniques
|
|
Concept
|
In Situ Hybridization, Fluorescence
|
|
Concept
|
Fatal Outcome
|
|
Concept
|
Exome
|
|
Concept
|
Embryonic Development
|
|
Concept
|
Chromatin Assembly and Disassembly
|
|
Concept
|
Smad4 Protein
|
|
Concept
|
Genomic Imprinting
|
|
Concept
|
Response Elements
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
Retinal Dehydrogenase
|
|
Concept
|
Platelet Count
|
|
Concept
|
Progeria
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Sarcoplasmic Reticulum
|
|
Concept
|
Brugada Syndrome
|
|
Concept
|
GATA4 Transcription Factor
|
|
Concept
|
GATA6 Transcription Factor
|
|
Concept
|
Kruppel-Like Transcription Factors
|
|
Concept
|
Inhibitor of Differentiation Protein 2
|
|
Concept
|
Epithelial-Mesenchymal Transition
|
|
Concept
|
High-Throughput Nucleotide Sequencing
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
Regulatory Elements, Transcriptional
|
|
Concept
|
Chemokine CCL4
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Heart Transplantation
|
|
Concept
|
Cyclosporine
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Death, Sudden, Cardiac
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Genes, Helminth
|
|
Concept
|
Genome, Human
|
|
Concept
|
Survival Rate
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Retinal Cone Photoreceptor Cells
|
|
Concept
|
Stroke
|
|
Concept
|
Gene Silencing
|
|
Concept
|
Gene Dosage
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Macrophage Inflammatory Proteins
|
|
Concept
|
Body Patterning
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Electrophysiologic Techniques, Cardiac
|
|
Concept
|
Transcriptome
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
AMP-Activated Protein Kinases
|
|
Concept
|
Haploinsufficiency
|
|
Concept
|
Organogenesis
|
|
Concept
|
Gastrulation
|
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
|
Concept
|
Sumoylation
|
|
Concept
|
Brain Ischemia
|
|
Concept
|
Chromatin
|
|
Concept
|
Crosses, Genetic
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Electrophoresis, Agar Gel
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Ethylnitrosourea
|
|
Concept
|
Genetic Testing
|
|
Concept
|
Genotype
|
|
Concept
|
Heart Rate
|
|
Concept
|
Heterozygote
|
|
Concept
|
Kinetics
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Staining and Labeling
|
|
Concept
|
Translocation, Genetic
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Mutagenesis, Insertional
|
|
Concept
|
Sequence Analysis, RNA
|
|
Concept
|
Regulon
|
|
Concept
|
Computational Biology
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
Genomics
|
|
Concept
|
Potassium Channels, Voltage-Gated
|
|
Concept
|
Databases, Nucleic Acid
|
|
Concept
|
Epigenesis, Genetic
|
|
Concept
|
Sarcoplasmic Reticulum Calcium-Transporting ATPases
|
|
Concept
|
Genetic Loci
|
|
Academic Article
|
Comparison of two murine models of familial hypertrophic cardiomyopathy.
|
|
Academic Article
|
Cardiac electrophysiological phenotypes in postnatal expression of Nkx2.5 transgenic mice.
|
|
Academic Article
|
Characterization of sinoatrial node in four conduction system marker mice.
|
|
Academic Article
|
Genome-wide identification of mouse congenital heart disease loci.
|
|
Academic Article
|
A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.
|
|
Academic Article
|
Combinatorial specification of blastomere identity by glp-1-dependent cellular interactions in the nematode Caenorhabditis elegans.
|
|
Academic Article
|
TBX5 drives Scn5a expression to regulate cardiac conduction system function.
|
|
Academic Article
|
E2F3 plays an essential role in cardiac development and function.
|
|
Academic Article
|
Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.
|
|
Academic Article
|
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
|
|
Academic Article
|
Inducible recombination in the cardiac conduction system of minK: CreERT² BAC transgenic mice.
|
|
Academic Article
|
Configuration of DNA strands and mechanism of strand exchange in the Hin invertasome as revealed by analysis of recombinant knots.
|
|
Academic Article
|
Hysteria in poliomyelitis.
|
|
Academic Article
|
Tetralogy of Fallot with congenital aortic valvar stenosis: the tetralogy-truncus interrelationship.
|
|
Academic Article
|
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
|
|
Academic Article
|
The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation.
|
|
Academic Article
|
Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
|
|
Academic Article
|
Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
|
|
Academic Article
|
Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
|
|
Academic Article
|
A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human.
|
|
Academic Article
|
Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics.
|
|
Academic Article
|
A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.
|
|
Academic Article
|
Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development.
|
|
Academic Article
|
Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis.
|
|
Academic Article
|
Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types.
|
|
Academic Article
|
Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq.
|
|
Academic Article
|
Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria.
|
|
Academic Article
|
Transcriptional Patterning of the Ventricular Cardiac Conduction System.
|
|
Academic Article
|
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
|
|
Academic Article
|
Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.
|
|
Academic Article
|
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation.
|
|
Academic Article
|
Chamber-specific transcriptional responses in atrial fibrillation.
|
|
Academic Article
|
Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types.
|
|
Academic Article
|
Control of cardiomyocyte differentiation timing by intercellular signaling pathways.
|
|
Academic Article
|
Author Correction: Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome.
|
|
Academic Article
|
Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome.
|
|
Academic Article
|
Identification of direct transcriptional targets of NFATC2 that promote ß cell proliferation.
|
|
Academic Article
|
Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development.
|
|
Academic Article
|
Differential Etv2 threshold requirement for endothelial and erythropoietic development.
|
|
Academic Article
|
Detecting critical transition signals from single-cell transcriptomes to infer lineage-determining transcription factors.
|
|
Academic Article
|
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
|
|
Academic Article
|
Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.
|
|
Academic Article
|
Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
|
|
Concept
|
Homeobox Protein Nkx-2.5
|
|
Concept
|
Zinc Finger Protein Gli3
|
|
Concept
|
Whole Genome Sequencing
|
|
Concept
|
NAV1.5 Voltage-Gated Sodium Channel
|
|
Concept
|
NAV1.8 Voltage-Gated Sodium Channel
|
|
Concept
|
RNA, Long Noncoding
|
|
Concept
|
Filamins
|
|
Concept
|
Atrial Remodeling
|
|
Grant
|
Functional Assays to Screen Genomic Hits
|
|
Grant
|
Functional Assays to Screen Genomic Hits
|
|
Academic Article
|
Tbx5 maintains atrial identity by regulating an atrial enhancer network.
|
|
Academic Article
|
ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment.
|
|
Academic Article
|
Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation.
|
|
Academic Article
|
The cGAS-STING pathway is dispensable in a mouse model of LMNA-cardiomyopathy despite nuclear envelope rupture.
|
|
Academic Article
|
An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract.
|
|
Academic Article
|
A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
|
|
Academic Article
|
Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network.
|